Cotswold Medical Practice is a ‘Research Ready Accredited Practice’ and member of the Primary Care Research Network. We participate in a variety of research studies that have been approved by the National Institute for Health Research (NIHR). This means we are working to find ways of improving the care we provide and help to inform future developments in health care.

You may be invited to participate, either by a letter through the post or during an appointment at the surgery. All clinical research is thoroughly checked and approved by ethical committees to ensure that it is appropriate and safe to perform. You will always receive clear information about what taking part in a research study would involve. Your participation is entirely voluntary and can be withdrawn at any time. You are under no obligation to participate in any research project and your care will not be affected in any way if you decided not to take part.

COVID-19 Studies

PANORAMIC Study (Finding new effective anti-viral Treatments for Coivd-19)

  • Tested positive for Coivd-19 and are experiencing symptoms starting in the last 5 days.
  • Age 50 or over? Or 19 or over with an underlying health condition?

Then you could join the Panoramic Study and help to find new treatments for Covid-19. PANORAMIC aims to find antiviral treatment to improve symptoms early and reduce hospital admissions for people with COVID-19.

Find out more: PANORAMIC Trial: Information

PRINCIPLE (Platform Randomised trial of Interventions against COVID-19 In older peoPLE)

It is open to all patients over 50 years old and is looking at the potential of existing medications as treatment for early COVID-19. If you start to develop any new COVID-19 symptoms, then please visit the study website (click HERE to view the PRINCIPLE study website).

Serology (blood sample) study. You may be offered the opportunity to provide an extra sample at your pre scheduled blood test. This is sample is being used by Public Health England (PHE) to look at the background immunity of the population to COVID-19. You will not receive any results from this blood test.

IMMUNE DEFENCE: This study will examine the effectiveness and cost effectiveness of commonly available nasal sprays and a brief physical activity and stress management intervention in preventing and reducing the incidence and severity and duration of respiratory tract infections among patients who may be at risk of serious infection during the COVID pandemic


Current Studies

SUMMiT-D (recruitment closed)

The aim of this trial is to compare the effectiveness and cost effectiveness of brief messaging to support patients with type 2 diabetes taking diabetes medicine (glucose, blood pressure, or lipid lowering) in reducing risk factors for diabetes complications, with usual care.


The REDUCE study looks at evaluating online support to patients and practitioners in the reduction of long term antidepressant medication for depression, together with some telephone support for patients.

Active Brains

This study compares a new website designed to help older adults look after their brain and body health with the aim of preventing cognitive decline. The website will help older adults make simple changes such as getting more active, playing brain training games and finding ways to eat more healthily.


The aim of this trial is to determine if screening for Atrial Fibrillation in people aged 70 and over leads to reduced incidence of stroke compared to usual care and what impact it has on outcomes such as effectiveness and cost effectiveness.

Clinical Practice Research Datalink

The practice is working with the Medicines & Healthcare products regulatory agency & National Institute for health research contributing anonymised data for the Clinical Practice Research datalink (CPRD).

CPRD data is used for approved medical and public health research including:

  • Investigating side effects of medicines
  • Investigating causes of disease and medical disorders and associated risk factors
  • Looking into the outcomes of treatments
  • Examining areas of unmet medical need
  • Identifying ways of improving screening or diagnosis
  • Evaluating which services or treatments work best
  • Find out more about CPRD at:

RCGP Research and Surveillance Centre


  • The practice is working with the RCGP research and surveillance centre contributing pseudonymised data for national research and important public health surveillance (Covid-19, Influenza etc.). This data enables continuous monitoring of infections and diseases in the community and is used in ethically approved research.
  • Find out more about RCGP at: